SECOND GENERATION VISCOSUPPLEMENT

INDICATED IN THE TREATMENT OF KNEE OSTEOARTHRITIS

HYALURONIC ACID + MANNITOL

HAppyVisc

MEDICAL DEVICE – 3 x 2 ml pre-filled syringes

High Molecular Weight

HAppyVisc™ is a visco-elastic gel which combines high molecular weight hyaluronic acid of 1.5 million Daltons and mannitol.

High concentration for prolonged activity

HAppyVisc™ contains high concentration of hyaluronic acid (1.55%) i.e. 31 mg/syringe. HAppyVisc™ brings 50% more hyaluronic acid than a traditional visco-elastic solution.

Mannitol

HAppyVisc™ contains high concentration of mannitol (70 mg/syringe).

Long-lasting effect: Mannitol is an anti-oxidant which protects hyaluronic acid chains from free radicals and limits their degradation increasing then their residence time in the joint cavity.

Analgesic effect: Due to its free radical scavenging properties, mannitol also ensures local analgesic effect.

Stabilizer: Because it is a thermal stabilizer, mannitol allows HAppyVisc™ to guarantee a stability of its rheological properties all along its storage.

Safe

HAppyVisc™ is highly purified and results from bacterial fermentation.

Experimental/Clinical studies

  • Decision Algorithms for the Retreatment with Viscosupplementation in Patients Suffering from Knee Osteoarthritis. Recommendations from the EUROpean VIScosupplementation COnsensus Group (EUROVISCO). R. Raman, Y. Henrotin, X. Chevalier, A. Migliore, J. Jerosch, J. Montfort, H. Bard, D. Baron, P. Richette, T. Conrozier. Cartilage. February-01-2017. Doi: 10.1177/1947603517693043 -Publication-