Addition of a Polyol to HA: a Significant Advance in the Treatment of Osteoarthritis?

Is the addition of a polyol to hyaluronic acid a significant advance in the treatment of osteoarthritis? Conrozier T. Curr Rheumatol Rev. 2017 Jul 10. doi:10.2174/1573397113666170710115558. Viscosupplementation with intra-articular injections of hyaluronic acid is recommended as a second line treatment for knee OA, after failure of non-pharmacological modalities and usual Read more…

Obesity, radiological severity and lack of response of viscosupplementation in knee OA

Viscosupplementation (VS) is still controversial. One of the key points is the lack of well-identified factors of response. The study “Obesity and radiological severity are associated with viscosupplementation failure in patients with knee osteoarthritis”, published in Journal of Orthopaedic Research this month, has been designed to identify clinical and radiological Read more…

Mannitol may shorten viscosupplementation onset of action in patients with knee OA: Read our paper

Addition of Mannitol to Hyaluronic Acid may Shorten Viscosupplementation Onset of Action in Patients with Knee Osteoarthritis: Post-Hoc Analysis of A Double-blind, Controlled Trial. Eymard F, Bossert M, Lecurieux R, Maillet B, Chevalier X, et al. (2016) J Clin Exp Orthop 2: 21. doi: 10.4172/2471-8416.100021 OBJECTIVE: To compare the speed Read more…