HAppyVisc® vs. Euflexxa®: Read our paper recently published in “The Knee”

Safety and efficacy of intra-articular injections of a combination of hyaluronic acid and mannitol (HAnOX-M) in patients with symptomatic knee osteoarthritis. Results of a double-blind, controlled, multicenter, randomized trial. T. Conrozier, F. Eymard, N. Afif, JC. Balblanc, V. Legré-Boyer, X. Chevalier, on behalf of the Happyvisc Study. The Knee. 2016. DOI: http://dx.doi.org/10.1016/j.knee.2016.05.015

The above mentioned clinical trial, conducted by LABRHA on 226 patients with knee OA and which compares the efficacy and tolerance of HAppyVisc® vs. Euflexxa®, has been very recently published in the well-known international journal The Knee (Impact Factor:1.446).

Results of this study show:

• HAppyVisc® was non-inferior to Euflexxa® for reducing pain and improving function
• There was a trend for a faster response with HAppyVisc® than Euflexxa® on pain
• HAppyVisc® was as well tolerated as Euflexxa®
• No severe adverse event related to HAppyVisc® was reported.

Keywords: Hyaluronic acid, Controlled trial, Knee osteoarthritis, Viscosupplementation, Mannitol, Intra-articular injection.