Safety and efficacy of single intra-articular injection of a mannitol-modified cross-linked Hyaluronic acid (Happycross) in knee osteoarthritis.

Safety and efficacy of single intra-articular injection of a mannitol-modified cross-linked Hyaluronic acid (Happycross) in knee osteoarthritis.

Abstract Objectives: To assess, in daily practice conditions, both safety and efficacy of a single intra-articular injection of a cross-linked hyaluronic acid (HA) combined with mannitol (HANOX-M-XL) in patients with symptomatic knee osteoarthritis. Methods: We analyzed the clinical and radiological data of 53 consecutive patients with symptomatic knee OA, treated Read more…

EUROVISCO Good practice recommendations for a first viscosupplementation in patients with knee osteoarthritis

EUROVISCO Good practice recommendations for a first viscosupplementation in patients with knee osteoarthritis

LABRHA is supporting Eurovisco by organizing its annual board since 2014. We are proud to be Eurovisco’s partner. Abstract Rationale Viscosupplementation (VS) with hyaluronic acid is widely used in the management of knee osteoarthritis. There is no clear recommendation on the decision-making to achieve VS. Design Based on extensive research Read more…

Study on viscosupplementation

The Association between Radiographic Features and the Duration of Effectiveness of a Single Injection of Extended-Release Hyaluronic Acid (HANOX-M-XL) in Patients with Knee Osteoarthritis.

  Preliminary Results of a Prospective Trial. Solène Perruchet, Jean-Charles Balblanc, Charles Rapp, Charlotte Bourgoin, Cerise Guillochon, Anne Lohse, Thierry Conrozier.   Background. Advanced radiological stage of knee osteoarthritis (OA) is predictive of poor response to viscosupplementation (VS). To date, the impact of x-ray features on the duration of effectiveness Read more…